We know during diagnosis of leukemia (B-ALL,T-ALL) , leukemia Blast  cells are seen in BM (20% and above)  and Peripheral Blood (10% and above).

We know this free floating blast that is seen in Peripheral blood in million are not having immediate threat of metastasis.

What metatstaic marker can help to distinguish free floating leukemia blast from leukemia blast that has the ability to form metastatic tumor in CNS,Spleen, liver etc. 

Will it be appropriate to use EMT marker to distinguish the free floating blast and  metastatic blast .