I have proteomics data and metabolomics data of the same sample set of a disease model. I have performed network/pathway analysis to each platform, but is there a good ways/tools/softwares to correlate proteomics and metabolomics regulations and even to genomics neworks? How dose real muti-omics network analysis work?
Thanks all for your input.
Hi,
you might want to check out this publication
Intuitive Visualization and Analysis of Multi-Omics Data and Application to Escherichia coli Carbon Metabolism
Brice Enjalbert, Fabien Jourdan, Jean-Charles Portais
PLOSne, 2011.
In general, you have two type of information to compute: "function" and "degree of (non)activity". In most cases, the first information is deducted by the presence of absence of a component in the network/system you are analyzing.
The degree of activity measures how much a network/pathway is activated or not. Here, concentration of the components is very important
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