How to dock and simulate multiple protein ligands on single RNA binding site simultaneously?

I have approx. 150 protein ligands and want to dock all 150 protein ligand on single RNA at a time. Is there any tool available for this particular purpose.

01 February 2019 4,450 2 View

How to prepare protein-ligand complex pdb for generating 2-D figure in LigPlot?

I have a pdb file of docked complex of protein and ligand from patchdock, but there is an error occurring when I am importing it to LigPlot.

01 February 2019 2,724 10 View

How to implement neomodal driver of python to implement neo4j database in my local website?

I need to integrate an existing neo4j-database into my django project using your package. Is there any best practice or things I need to consider to do this?

10 November 2018 9,306 0 View

What are the way to retrive data from different columns of existing tables in database by selecting checkbox through php?

I have a multiple checkbox (about 40) in search form of my website. This checkbox contain names of tables stored in database. I am unable to fetch data from columns of the tables in database by...

07 August 2018 4,176 1 View

How to implement graph network built on neo4j browser into our locally built website?

I built a network graph between RBP and non coding element on the basis of positive and negative value of correlation which is statistical parameter on neo4j browser. I just want to impliment this...

07 August 2018 4,494 2 View

How to retrive multiple data stored in database using checkbox through php?

I made a website where in my search page. I gave checkbox option to retrive data which are stored in our database. when I click on multiple checkbox, I am unable to find the result. what can I do,...

07 August 2018 4,769 3 View

Anyone please tell me how to built RBP-miRNA interaction regulome model?

Q-How can we construct RBP-miRNA interaction base gene expression regulatory network from CLIP-seq ,RNA-seq and miRNA seq data?

05 June 2018 4,902 4 View

How to write cypher query for neo4j graph database of my sample data file containing 7 different column ?

I have a sample data file which contain following data: hsa-miR-101-3p hsa-mir-101-2 AGO1 AGO2 NA NA NA hsa-miR-101-3p hsa-mir-101-2 AGO1 AGO3 NA NA NA hsa-miR-101-3p hsa-mir-101-2 AGO1 AGO4 NA...

05 June 2018 8,929 1 View

How do I run a Python script on my web server?

06 July 2017 7,836 1 View

What is the reson for descripancy found in evaluatric parameter for built model?

02 March 2017 9,083 0 View

How to compare two groups with only two measurements?

Hiiiii everyone! I have an enquiry on statistical analysis. I was looking for many forum and it's still cannot solve my problem. I want to compare means of two groups of data but only with two...

03 March 2021 8,796 3 View

What's the best way to measure growth rates in House sparrow chicks from day 2 to day 10?

What's the best way to measure growth rates in House sparrow chicks from day 2 to day 10? Since, the growth curve from day 2 to 10 won't be like the "Logistic curve" it might not follow logistic...

03 March 2021 1,401 3 View

How to increase a model accuracy ?

dear community, my model is based feature extraction from non stationary signals using discrete Wavelet Transform and then using statistical features then machine learning classifiers in order to...

03 March 2021 6,994 5 View

1. What is the impact of having different scales in a survey? and how can we solve this problem before and after data collection (Literature)?

1. What is the impact of having different scales in a survey? and how can we solve this problem before and after data collection (Literature-based reflection)? Thank you for your time and for...

03 March 2021 2,870 3 View

What degree of missing data in a particular case/participant results in Expectation-Maximisation no longer working?

I'm dealing with a mediation model and am using the PROCESS module in SPSS. Due to SPSS and PROCESS being limited in the imputation methods - being unable to handle multiple imputation - the other...

02 March 2021 4,362 1 View

Can NFL theorem be valid in infinite search space in ML?

NFL theorem is valid for algorithms training in fixed training set. However, the general characteristic of algorithms in expanded or open dataset has not been proved yet. Could you show your...

01 March 2021 1,189 3 View

Does anyone know how to plot my station to a section plot on Ocean Data View (ODV)?

I made a vertical section plot with WOA .nc file on ODV, and now I want to plot my stations (csv. file) in it. Does anyone know how to import my points to the section? They are two different...

01 March 2021 3,610 1 View

How to address this issue in the analysis of Real-Time PCR results?

To dear Researchers, I was analyzing a series of concentration for estimation of Real-Time PCR efficiency. The concentration was 1:10. I used MS-excel to evaluate Slope. The result of slope was -8...

01 March 2021 8,683 4 View

Can I download BibExcel for MacOs?

Hi everyone, I would like to ask how I can download BibExcel software for MacOs? There are some links which are supported by Windows but I could not find it for Mac. or is there any other software...

01 March 2021 652 1 View

How to arrange coordinates and extract climate dataset out of MPI-ESM-MR netcdf files?

Have a nice day everyone, I'm stuck in extracting datasets out of MPI-ESM-MR netcdf files because the latitude ranges from -3*10^6 to 3*10^6 and longitude ranges -5,9*10^6 to 5,9*10^6. Plus, the...

28 February 2021 912 3 View