01 January 1970 1 669 Report

After extracting mutational signatures observed in a dataset of SNVs. I want to determine which COSMIC signature does the extracted mutational signature is close to.

More Nikita Naik's questions See All
How to highlight novelty in your research paper?

I have come up with a method and had written a paper on it. Paper got rejected by a journal stating that there is no theoretical novelty. I am kind of confused on why the novelty that I am able to...

28 February 2021 2,393 8 View

I have genotype gvcf of 30GB , which is causing an issue in analysis. I was wondering if there is a way to get around the size issue ?

I have a genotype gvcf of significant size, which is causing an issue in analysis. I was wondering if there is a way to get around the size issue and run the genotype gvcf in R or do I need to...

09 February 2021 4,178 4 View

Can anybody please give me idea about the complete procedure to estimate state of charge of the battery through hardware setup?

I am working on SOC estimation of battery for EV's, I want to extract the real battery data through the experiments on battery, so i want to know what exactly the equipment's i need to perform the...

22 January 2021 8,216 2 View

How stiffness matrix modification after hinge formation is done for pushover analysis?

Can anyone please explain this? How do I account for plastic hinges in my model and how do I modify the stiffness after plastic hinge is formed? Need a small example. Thank You

15 November 2020 1,967 3 View

How to analyze nominal/ordinal data in cases where you are testing multiple drugs/ infection against common risk factors?

chi-square or Fisher exact test I have a statistical question about chi-square and/or Fisher exact test. I have a cohort data studying the cause of infection in BRD with variables such as age,...

28 October 2020 2,589 1 View

What vehicle to be used for the drug loaded nano chitosan-pectin nanoencapsulated powder?

I want to know about vehicle or solution that I can use for the dosing of drug loaded nanochitosan-pectin nanoencapsulated powder?

25 October 2020 3,890 3 View

How to use 5 by 5 or 7 by 7 kernel size for a deep learning network with 3 by 3 kernels?

I am using a U-Net architecture with Xception net as encoder . The visual area of the segmentation mask is very small and after training, it is giving a lot of false positives. I am thinking of...

20 September 2020 1,968 2 View

How to model hysteresis property of concrete in abaqus?

I want to model rc element subjected to cyclic loading, How do I enter hysteresis data in the material model? I want to use Mander's 1988 model to get data for concrete. I dont know how to enter...

06 September 2020 7,651 3 View

Which fractional operator (with singular/nonsingular kernels, local, discrete, etc.) is more effective for modeling biological systems/processes?

To identify the most important fractional operator which is physically significant for the modeling of biological systems/processes (Viral dynamics, Fluid dynamics, Calcium dynamics and so on) to...

08 July 2020 8,146 3 View

Column chromatography. Problems with pH - why?

What if in column chromatography with solution (neutral pH) acidic pH is observed and remains along the whole process? What went wrong and what to do with this?

10 April 2020 5,587 4 View

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Hi, I want to start testing pitfall trap to obtain ants samples, but I need to conduct molecular analysis on those insects. So, what kind of fluid can I use? Ethanol expires too early and I need...

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What's the best way to measure growth rates in House sparrow chicks from day 2 to day 10?

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Do we need to write protocol for a second study of a systematic review that has been registered and published?

I have conducted and published a systematic review and meta-analysis research with the topic related to public health and health pomotion (protocol was registed in PROSPERO). Now we want to...

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How to increase a model accuracy ?

dear community, my model is based feature extraction from non stationary signals using discrete Wavelet Transform and then using statistical features then machine learning classifiers in order to...

03 March 2021 6,994 5 View

Do I need to do linear regression before running mediation analysis using PROCESS MACRO by Hayes ?

I just wanted to check if I need to run a linear regression separately if I am using PROCESS MACRO to run mediation analysis. Thank you.

02 March 2021 4,359 3 View

What are the most reliable approaches to extract key continuous frames from a video, with complete automation?

I have an input video, of skin (from a microscope that means it is magnified such that blood capillaries are visible). The idea is to extract 15 sec of continuous frames from a video of 1 min,...

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Sample dilution for quantitative analysis using ELISA?

If the detection range is in ng/ml but the reference range is in ug/ml for a molecule or protein in serum or plasma .how to dilute and what is the initial volume to be taken for quantitative analysis

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