I use R to do univariate regressions for a large data set consisting of 6000 variables. I would like to know whether checking the homogeneity of variance is necessary for large sample or not. Also, what is the best way to check for homoscedasticity in such a large data set and how to solve the probable heterogeneity of variance in those variables as it is too time consuming to use logarithm transformation for each of the variables.