The aim of my research is to analyse the correlation between two delta values (change between two timepoints) via regression analysis.
Let the variables be X, Y, and Z, and t0 represent pre-intervention and t1 represent post-intervention. X is a psychometric value (Visual Analogue Scale ranging from 0 to 100), Y and Z are biological values.
For example, I want to calculate the correlation between delta (Xt1 - Xt0), delta (Yt1 - Yt0), and delta (Zt1 - Zt0).
I am aware that delta value is statistically inefficient, therefore Pearson's correlation or Spearman's correlation is out. I would appreciate any advice or any model examples. Thanks!