I am trying to add bioglass nps in SA/CH blend solution using following weight % ratio:
1. SA/CH/BG: 60/40/1% : SA/CH blend solution is 100ml and 1gm Bioglass
Problem I am facing: I have to print that composite solution into 3D scaffold that require a minimum printability of that solution. To accomplish this, I mixed bioglass (1gm) in SA/CH blend solution and kept for 12 hour for complete mixing (digital image attached with this file). After mixing the solution I found that a white precipitate , which was not as per my requirement.
How can I mix the bioglass in the solution so that I can print that composite slurry or solution in form of 3D scaffold.
This is a tough problem and there can be many ways to solve it. Can you add a stabilizer? Can you heat the solution? Can you stir it for a long time (this might increase the deposition time)? Can you reduce the quantity of the nano components? I guess you have to spend some time and try all the options available. Good luck
I don't see where you explain what is the carrier of your slurry. You only mention three ingredients that are basically all powders.
And as to the BioGlass, I believe that this material has to be kept in a dry environment as it is known to absorb moisture.
I agree Ca ion effect on the gelation of alginate. However, if you have a homogeneous solution, you will have a strong hydrogel. Most probable you cannot mix bioglass homogenously in your polymer solution. First, you should understand how bioglass acts in water with different pH. Chitosan dissolves in an acidic environment so you should have stable bioglass dispersion in these conditions. Similar understanding is needing how alginate chitosan solution acts in these conditions. If your bioglass is not stable (stability, zeta potential > 30 mV or
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