Gene regulation and environment are quite related with each other thats why the circadian rhythm is maintained but what are the exact factor for that specific gene expression and the molecular mechanism behind detecting the environmental changes by the human body?
Kou Hayakawa
, Sir thank you for your answer and recommendation, I got a hint to my question, I would like to express once again my question through an example: two genes in Drosophila melanogaster such as TIM and PER are quite dependent upon the day and night cycle for the expression so that what is the facctor in the day and night cycle which is determining the expression of both genes individually that is what confusing and if those set of factor could be manipulated in the cancer cell microenvironment to revive the cellular circadian rhythm rather than killing the cencer cell with chemotherapy that could be a right way to approach cancer biology in present scenario?
Ok Sir thank you for your time!! I will move through all these recommendations.
Ok sir, In my case Cancer cell has severe alteration in circadian rhythm also in all cancers, it may be leading to change in protein expression, then how do I proceed to know that circadian rhythm genes and thier product could or could not reviving the cancer cell microenvirionment.
Unfortunately, till now I did not have a study in this field.
I use comments. Thanks
With the best wishes
Mr Rezaei Ahvanooei.
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