BBB we know prevent bacterial & viruses crossing but how Drug can pass through BBB & what is the role of Passive transport in it. Kindly explain it Diagrammatically preferably.
The transport routes across the Blood Brain Barrier (BBB) is through passive diffusion, passive solute carrier (SLC) mediated delivery, receptor-mediated transcytosis (RMT) and adsorptive-mediated transcytosis (AMT) occurring in both directions from blood to brain and from brain to blood.
The highly lipophilic compounds with small molecular sizes (