Recently, there are studies demonstrating the effect of NPs for enhancing productivity in fermentation processes. However, the long term impacts of nanoparticles to living organisms including humans needs to be thoroughly evaluated. In this context, how much safe is the use of nanoparticles (NPs) in bioprocess technology and biomedicine?
Hi GSD. I think you have partly answered your question yourself. One should evaluate both environmental impact and nanotoxicological profiles of nanoparticles in question. IMO it is better to remove nanoparticles during downstream processing if the productivity of nanoparticle-mediated fermentation is very high. It will be a tough task but it is not impossible. Off the top of my head i can think of a density centrifugation based method if densities of product and nanoparticles are different. I hope I've answered your question.
-vish
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