How much maximum biomarkers may be combined to get earliest starting of bone loss due to chronic periodontitis in human?

More Satish Narula's questions See All

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Rekha Rani Koduganti

Perhaps alkaline phosphatase , ICTP and osteonectin could help as markers of initial bone resorption.

Andrea Chen

Maybe can use the technology of alternating impedance spectroscopy such as similar principle as CarieScanPRO in periodontal probe to detect patients' gingival crevicular fluid (GCF) and bone...

Muhammad Saad Shaikh

I agree with Rekha’s answer.

If gingiva stared interrupted inflammation and its gingival crevicular fluid (GCF) had high dose of M∅ which has potent derivate to osteoclast, maybe it's the earliest sign of periodontal bone loss although bone loss (demineralization) is too tiny to be checked by X-ray film.