How many marker compounds must be analysed for Standardization of a single herbal Drug and for compound formulation ?
Basically it depends upon your aim & objective. If you want to analysed then go for those markers which contain highly in that drugs
If you want to analyze the drug for analytical purpuses, such as HPLC, UPLC, etc. (quality assurement) there are no rules for the number of analytes; however, it is recommended that they are chemically defined and, if posible, specific for the species, they can be either active or not.
If you want to standardize the extract for the activity, you should focus on the active compounds, usually from one to three compounds are preferred, since the methods are to be repeated several time, simplicity is desired. In that way, you could make mixtures of different samples to produce a standardized extract.
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