I guess , for your question, that you intend to measure biomarkers in plasma. You have to be sure it's the best type of sample for measurement , because it is not always so.
The most obvious answer is that the separacdión should be as quick as possible. However, in the case of epidemiological studies is often blood drawing is not performed close laboratory instrumentation . One solution is to equip field devices with small centrifuge that can perform this function.
Moreover, do not tell us what kind of work you intend plasma (Li- heparin , some form of EDTA, ....) , nor what kind of biomarkers want to measure : there are some that are very sensitive and require even use of antiproteases to avoid rapid degradation , while there are others that are more stable and can withstand a bit of time without plasma separation .
Anyway, as I said earlier , it is best that the separation is as fast as possible