How to Remove different version of atom from pdb Crystal Structure for Docking Preparation?

I am new to Docking and MD, and currently try to catch on it. I try one of the webserver for docking, but unfortunately not working. it says " Your PDB contains multiple forms of the same residue...

08 February 2021 7,426 3 View

What makes a strong research question?

A good research question is essential to guide your research paper, project, or thesis. It pinpoints exactly what you want to find out and gives your work a clear focus and purpose.

25 December 2020 6,145 4 View

Does Neighbor-Joining (NJ) clustering method suitable to cluster the water quality data?

Dear researchers, I'm using a software called PAST to analyze my multivariate water quality data. For clustering the sampling stations using 14 water quality variables, I found that NJ with...

27 July 2020 2,972 3 View

Do you know what is TCGA database?

Hello, Do any one know how TCGA database works? any tutorial to show ho to use it and interpret the data? Also, any idea about any database website that shows the expression level of specific...

29 August 2016 1,493 3 View

Why I couldn't detect it ?

18 June 2016 2,081 3 View

What is the relation between the number of people and the temperature in the room?

05 June 2016 8,300 8 View

Hello,I am looking for a database bioinformatic tool to show the expression of microRNA in normal and malignant breast tissue?

Hello,I am looking for a database bioinformatic tool to show the expression of microRNA in normal and malignant breast tissue, Thanks

11 May 2016 4,951 3 View

Is there any difference on primary antibody binding region?

27 January 2016 6,179 2 View

How can I distinguish between Ce4+(CeO2) & Ce3+(Ce2O3) as promoter in the catalysts?

09 June 2015 1,320 6 View

Why can't Dragendorff's reagent precipitate caffeine?

See above

26 May 2014 232 1 View

Do I need to introduce HFD to ob/ob mice to obtain a T2DM model?

I am planning to work on T2 diabetic animals and check the efficacy of probiotics. My initial plan is to fed B6 animals with HFD for a while. But now, I have the chance to work on ob/ob mice. My...

18 February 2021 6,896 3 View

What is the reason of more than 50 % mortality while I am using Streptozotocin for induction of diabetes at proper dose??

My research work is to evaluate wound healing effect of different compounds in diabetes rats. For this purpose I used Streptozotocin drug at proper dose. After diabetes induced in rats we created...

25 June 2020 2,144 1 View

Rat or mouse, which one is better for making diabetic nephtopathy model?

Dear All we want to develop a diabetic nephropathy model. But I wonder if you may have a recommendation for us. My question is that if our team should go over mice or Rats? Thanks!

11 December 2019 7,431 3 View

Validation for Intracerebroventricular Microinjection of Streptozotocin in Rats?

Hi, I'm planning to induce sporadic Alzheimer's disease (AD) in male Sprague Dawley rats (3 months old, 270-350g) through bilateral intracerebroventricular microinjection of 3 mg/kg streptozotocin...

25 November 2019 9,723 3 View

Is it possible to decrease the ITGB1 gene expression level in peripheral blood in diabetic neuropathy patients?

According to our research, we have found expression of miR-183-5p reduced in peripheral blood in patients with diabetic neuropathy, and ITGB1 is one of the targets of miR-183-5p. Therefore, its...

10 November 2019 5,800 3 View

Is it possible to decrease the ITGB1 gene expression level in peripheral blood in diabetic neuropathy patients?

According to our research, we have found expression of miR-183-5p reduced in peripheral blood in patients with diabetic neuropathy, and ITGB1 is one of the targets of miR-183-5p. Therefore, its...

02 November 2019 618 3 View

Where can I find the Diabetes Screening Complications Research Initiative (DiabHealth) database of ECG recordings?

Many articles have used the large database of health-related parameters and tests amalgamated in the Diabetes Screening Complications Research Initiative (DiabHealth), but I cannot find it online....

27 October 2019 5,959 2 View

How much time it takes to develop a complete STZ Induced Diabetic mice model to start testing Therapeutic drug?

STZ Induced Diabetes

14 October 2019 3,878 3 View

How much time it takes to develop a complete STZ Induced Diabetic mice model to start testing Therapeutic drug?

STZ Induced Diabetes

09 October 2019 7,386 2 View

How do I co-relate between diabetis and glaucoma?

Hi all, want to ask if there is any simpler way to co-relate between diabetic neuropathy and glaucoma? What is the mechanism or what is being affected in diabetic patient that leads to the...

16 September 2019 9,373 5 View