Need methods for Formulation and evaluation of anti-aging cream, gel and serum?

Can anybody provide me standard methods for the formulation and evaluation of herbal anti-aging gel, cream and serum with accurate formula? My goal is to develop three (as said above) individual...

03 April 2019 7,993 4 View

Calculation of Sample concentration using AUC in HPLC?

How to calculate sample concentration and percentage by using AUC of sample and AUC of standard? I ran standard and samples at same conditions in HPLC and have good resolution of peaks. Can...

06 July 2018 3,472 0 View

Can anyone working in the chemistry of blue dye obtained from Indigofera or other plant species?

Is anyone working in the chemistry of Indigo blue dye who suggest me the possibilities to get indoxyl glycoside (Indican) from blue indigo dye? I mean i want to do reverse process i.e. conversion...

04 May 2018 3,658 0 View

Can anyone suggest how I can crystallize the compounds from pet. ether fractions collected by CC?

I run a column of pet. ether extract and collected 25 fractions from pet.ether: ethyl acetate (80:20) mobile phase. One fraction showed single spot on TLC in same solvent system but difficult to...

04 May 2014 565 10 View

Can any one suggest how to determine the percentage of solvent present in any extract?

I extracted plant material with ethanol for anticonvulsant activity. DMSO is used to dissolve the ethanolic extract. But ethanol itself has CNS stimulant activity. So please suggest a method by...

31 December 2013 1,709 11 View

What happened when excess silica gel is added to the methanol extract before column chromatography?

I have added silica gel in excess amount for column chromatography in methanol extract. Can anyone tell me, can this create any problem during running of column? If yes, what is the solution?

10 November 2013 5,161 7 View

How do I crystallize compounds isolated through water extract by preparative tlc and how do I separate dissolved silica gel from water fraction?

Using Preparative tlc. I elute two fractions (Methanolic and Watery) from water extract of tubers of a plant. Both fractions are reddish color but in water fraction there is a small amount of...

02 March 2013 1,332 9 View

Can I perform LCMS or any other Instumental analysis of a watery eluted fraction which helps in identification of a particular compound?

Is mass spectrum helpful in clearly identification of compound?

02 March 2013 3,135 2 View

How to address this issue in the analysis of Real-Time PCR results?

To dear Researchers, I was analyzing a series of concentration for estimation of Real-Time PCR efficiency. The concentration was 1:10. I used MS-excel to evaluate Slope. The result of slope was -8...

01 March 2021 8,683 4 View

Can I download BibExcel for MacOs?

Hi everyone, I would like to ask how I can download BibExcel software for MacOs? There are some links which are supported by Windows but I could not find it for Mac. or is there any other software...

01 March 2021 652 1 View

Anyone with some Transgenomic Wavemaker software? Seeking help from the chromatography community?

I am trying to seek out some Transgenomic Wavemaker software (happy to purchase a computer too) to operate a fraction collector. The only way to connect to the fraction collector so far is to...

23 February 2021 9,181 1 View

I am looking for a simple software program to model 3D chemical bonds. The purpose is to generate high-quality graphical abstracts. Any suggestion?

Hello everyone: I am looking for a simple software program to model chemical bonds. The purpose is to generate a high-quality graphical abstract for a top leading journal in the field of...

23 February 2021 8,012 3 View

Best excel chart to compare algorithms' running time?

Hi I want to compare the running time of robotic path planning algorithms. The grid size is 8X8. I have 100 scenarios of start and goal positions.. Each scenario is run in three obstacles ratio...

22 February 2021 621 1 View

Phenol-pH graphic?

We want to use phenol pH graphic to measure the pH of mediums before and after inhibitor application to cells. We have phenol absorbence values at 460, 560 and 720 nm wavelength. When we measure...

20 February 2021 7,700 3 View

How to open an old ".MTS" file containing spectroscopic data?

Hi supreme hive-mind of the internet, we have some old *.MTS files that are supposed to contain spectroscopic data, probably some coordinates and a long list of single line spectra. Basically,...

16 February 2021 9,385 2 View

Room Occupancy Calculation ?

15 February 2021 1,997 6 View

Analyze anthocyanin use pH differential method?

Hello everyone. I do my anthocyanin test for biscuit incorporated with muntingia calabura fruit powder. I use ultrasonic bath for extraction biscuit powder in metanol HCl 0,1 N (1:10, w/v),...

10 February 2021 2,970 13 View

How to check if the PMF profile obtained from ABF simulation is correct?

I am doing ABF simulations to calculate ligand binding enegy. The PMF profile that I get using single long ABF simulation is attached as pmf_total.png. When I do this ABF calculation with 10...

10 February 2021 4,170 2 View