Thanks for your interest and for recommending my question.

Alpha lipoic acid is a very promising drug according to literature and videos. We need to understand how to use it.

If we can interchange links or good paper titles? It might help.

Not surprising.

Irradiation causes cancer and treats cancer -;)

It is a good try Dr. Peter.

My aim of the question is to discuss it for a better understanding of proper use of alpha lipoic acid.

I can suggest a possible explanation which is related to its chelating action on neurotoxic heavy metals like mercury, taking them away from the brain cells.

Alpha lipoic acid carries mercury, and due to the short half life of it, at a time mercury falls on vessel walls if alpha lipoic disappears from blood stream leading to a vascular reaction (migraine).

I am trying to stimulate discussion on understanding alpha lipoic acid. What is said "that no side effects detected" can be inaccurate.

The above explanation above is of course not mine. I t came out after my search many weeks after I raised the question. I would not put a question which its answer is known to me.

I am opening it now for further discussion and criticism to clarify it more.

I believe the answer is to add Chlorella (~2000 mg) to bind the chelated metals once freed after the alpha lipoic acid has been metabolized. Also, the conditions mentioned could also benefit from liposomal glutathione and precursors glutamate, glycine and cysteine. Other glutathione cofactors (as alpha lipoic acid) could fit into the interactions to benefit as well: vitamin C, vitamin E, vitamins B1, B2, B6, B12, folate (B9), minerals selenium, magnesium and zinc.

I agree with Dr. Rich

Thanks Dr. Rich,

Kindly give me references

How to use all this together?

What is the duration and doses? Should we use all minerals and vitamins mentioned?

For how long can alpha lipoic acid be used? Any withdrawal plan?

U should ask you’re Pharm instructor or see a licensed provider for a proper intake/workup. No situation is same as any other to patient is the same as any other

Very good advice Dr Anise. Can you give good guidelines references about its use in diabetic neuropathy, and neurodegenerative diseases.

Once again advice on Guidlines or use of the different guidelines are specific to individual cases. If you are just wanting basic guidlines irrelevant to specific cases those are readily available by the Alopathic community and easily searched on PubMed or by just doing a google search. No competent practitioner would use any guidlines anywhere unlessuseless unless the entire current medical picture with past medical history is known to add Signs and symptoms into the google search should get you what u want...

Thanks Peter for your answer and sorry for delay as I was busy with Quran question. What I understood is that you prefer using fish oils instead of ALA.

On reading your profile, I found you are much more specialised in cell energy.

Do you agree on claimed benefits of ALA?

Best regards,

Sorry I missed your reply. I will answer as best as I can.

You said:

Kindly give me references

How to use all this together?

What is the duration and doses? Should we use all minerals and vitamins mentioned?

For how long can alpha lipoic acid be used? Any withdrawal plan?

I reply:

The attached document may be helpful in a general way. Liposomal glutathione could help to pick up the slack when withdrawn (personal inference).

NIHA Dosing with Chlorella/Cilantro for Neurotoxin Elimination:

https://www.nihadc.com/library/detox-for-life-class-2-addit-resources/54-4-dosing-with-chlorella/file.html?accept_license=1

Mercola:

https://articles.mercola.com/sites/articles/archive/2010/07/03/chlorella-shown-to-remove-mercury-in-mice.aspx

Chlorella acts as an efficient detoxification agent by binding to toxins, such as mercury, in your body and carrying them out of your system. It is the chlorophyll in chlorella that makes it so powerful, as chlorophyll helps you process more oxygen, cleanses your blood and promotes the growth and repair of your tissues.

Top brands and confirmation of binding effects:

https://www.naturalnews.com/044369_chlorella_heavy_metals_mercury.html

Secondary support for mercury chelating effects:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4055906/

Vit. C impedes action. See link one for details.

See: Xue HB, Stumm W, Sigg L. The binding of heavy metals to algal surfaces. Water Res. 1988;22:917. doi: 10.1016/0043-1354(88)90029-2

Side effects and safety studies:

https://examine.com/supplements/alpha-lipoic-acid/

Thanks too much Rich. You used to be very generous with me dear friend. I will come back after some days.

By the way how to search for you? Your opinions are very valuable.

In response to adding anything to an intravenous ALA, per Dr. Burt Berkson, MD, PhD, the creator of the IV ALA N protocol, the answer is a resounding NO! Vitamin C and ALA can lead to a precipitate that can lead to a CVA. ALA is always administered alone in D5W. Can cause a short term hypoglycemia. No IV dose over 600 mg. May damage mitochondria over 600 mg. Good luck.

Michael,

You are raising up 2 very important precautions for further studies:

Use of concomitant vit C.

Dose of ALA

I appreciate,

I may have litle/no understanding on lipoic acid as a cause and a cure of migrain but I do know that remedies work when taking according to prescription. Most drugs are synthesized from microbes that cause diseaese yet they work to cure the same. When remedies are not properly applied, there might be development or even led to the disease developing resistance towards the drug that suppose to cure it.

I agree Segun. The application of your principle on ALA would be ensuring enough chelation by dosing or to combine other chelators as suggested by Rich above. This hopefully would avoid precipitation of mercury over arterial walls which causes severe headache.

ONE PRECAUTION is that my answer is not an expert one.

Again, per Dr. Berkson, if one does IV ALA for chelation purposes it would also be important to also do concomitant oral ALA to prevent the ALA from literally dropping a chelated metal at a site other than bile or the kidneys. ALA is both fat and water soluble so it can cross the blood brain barrier.

Very important. Can you mention the reference details?