04 October 2023 1 5K Report

Are globular proteins able to bind to ANS in a folded or unfolded state?

More Timofey Shiryaev's questions See All
How do different types of parasites interact with each other within the same host?

Are parasites capable of entering into symbiosis with each other? There are multipartite viruses, the genomes of which are distributed over several capsids and For the infection to proceed...

15 October 2023 1,703 1 View

What are the best discretization methods for simulating devices with sharp interfaces?

I am trying to simulate electronic devices with sharp interfaces such as bilayer organic solar cells and diodes under the high applied voltage regimes to study the physics of their breakdown....

11 October 2017 8,142 3 View

Is there a simple way to make hydrophobic PMMA film?

Does the solvent used have an effect?

16 February 2016 6,516 7 View

Is there any significant difference between the film made from PMMA dissolved in chlorobenzene and that from PMMA dissolved in dichloromethane?

I am attempting to use the process described in the link below. Briefly, one spin-coats PMMA onto the substrate that has nanostructures on it. Then put PDMS on top and add a few drops of water...

05 February 2016 559 4 View

What is the best method to make a 1-2mm thick PDMS stamp out of Sylgard 184 Silicone Elastomer Kit?

I have seen procedures suggesting repeat spin-coating and curing. Others suggest simply pouring into a mold to desired thickness and curing.  I would like to use the stamp for transfer of...

09 January 2016 739 10 View

Similar questions and discussions
How to prediction 2D to 3D aptamer?

Hello, I have a little problem. Well, right now I only have the DNA aptamer sequence. I went to see the 2D model form with DNA folding. After that, I used RNA Composer to simulate in 3D and used...

30 July 2024 6,794 0 View

What is an ideal threshold value for log2(fold change)?

Hello everyone, I am performing differential gene expression analysis and I am not sure what is an ideal threshold for log2(Fold change).Thanks in advance!

09 July 2024 1,437 1 View

Unexpected Increase in R² for the Third Component in sPLS model?

Hi everyone, I'm performing a sparse Partial Least Squares (sPLS) model to understand if the analysed contaminants (55 individual contaminants) explain my response variables (42 response...

07 July 2024 2,333 0 View

What is Ala Vestibuloplasty dog technique?

procedure in which both the axial portion of the alar wing and all of the alar fold are removed by amputation. The procedure results in a very cosmetic appearance when done properly.

16 May 2024 9,828 0 View

How have solitons been interpreted in the protein folding mechanism?

One and two soliton solutions have been obtained while considering the protein folding mechanism of Davydov solitons. What are the dynamics of these soliton solutions that can be obtained in...

25 April 2024 5,241 0 View

Can a potent form of Caffeine be made?

Is it possible to do a Structure Activity Relationship for Caffeine given that it's structure is similar to that of Adenine. Maybe analogues can be made using caffeine as lead compound....

22 April 2024 8,476 0 View

How to quantify active or folded protein left after exposure to DMSO?

I am working on an enzyme and checking its stability in different solvents. One of the solvents is DMSO. I am interested in checking how much active or correctly folded protein is still in the...

24 March 2024 1,843 6 View

FOLD CHANGE calculation for metabolomics data?

I have metabolomics data from a non-targeted approach normalized with internal standards. I have calculated the p-value (t-test), VIP score, and fold change. For that, I transformed the data (each...

23 March 2024 9,663 1 View

Functional/non specific disulphide bond formation in proteins?

As an alternative to looking at the conservation of cysteine residues amongst homologs of a protein of interest, is anyone aware of a server that can predict whether disulphide bond formation...

21 March 2024 3,803 1 View

How to compute a ∆∆Ct analysis for bacterial growth?

Hello, I am quantifying bacteria exposed or not to a certain chemical at specific time points. How can I compute the results in a relative manner? That is: what is the formula for a ∆∆Ct analysis...

10 March 2024 6,322 4 View

Our partners will collect data and use cookies for ad personalization and measurement. Learn how we and our ad partner Google, collect and use data. Agree & close