In Pharma Industry: In cleaning validation, how do we calculate MACO for multiproduct facility? (since the factors like worst case scenario and the minimum batch size may be different for different product). For example, let's say there are 4 equipments in a production line namely 1, 2 ,3, 4 whereby 1, 2 and 3 is used in production of A and B product except 4 is used in the production of B product only. in this case, how to calculate for the MACO limit? is there any formula for calculating MACO for multiproduct facility? thank you.

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