Any successful story for the bio-degradation of Thiocyanate from laboratory to Field ?

Because many scientist groups are working on this problem. Success rate at laboratory level had been reported but at field level hardly we will find any story.

10 November 2017 9,028 0 View

Anyone familiar with MD simulatios using Gromacs ?

I have a .pdb file, in this file when I want to use pdb2gmx command> there is this error massage:> Fatal error:> Incomplete ring in HIS680Ask What should to do?

06 July 2015 5,114 12 View

Can anyone help with MD simulations using Gromacs?

During add ions steps using Gromacs the overall charge on my protein was calculated qtot -35 So i have to add positive ions to neutralize the charge on protein. then i have added 35 Na ions using...

06 July 2015 4,497 3 View

MD simulatios using Gromacs?

During MD simulations i got fatal error during energy minimization step after commend: gmx grompp -f minim.mdp -c 2HQA_modified_solv_ions.gro -p topol.top -o em.tpr Fatal error:number of...

06 July 2015 1,963 2 View

Does anyone know how to operate GROMACS software for analysis of molecular dyanamic simulations using ubantu operating system ?

06 July 2015 4,134 3 View

MD simulations using Gromacs?

During MD simulations i got fatal error during energy minimization step after commend: gmx grompp -f minim.mdp -c 2HQA_modified_solv_ions.gro -p topol.top -o em.tpr Fatal error:Too many warnings...

06 July 2015 6,067 4 View

Can someone help me to short out the problem regarding smear on gel of PCR product?

07 August 2014 2,198 8 View

Please suggest me any journal name to publish my work on in silico (Bioinfomatics) hypothesis regarding adaptation between impact factor 1 and 2

Computational approach

11 December 2013 9,861 2 View

Xylanase bacterial enzyme

I am just starting work on xylanase. Can you suggest an appropriate site for sample collection of xylanase?

05 June 2012 2,534 6 View

How to analyze a particular region of my simulation box in GROMACS?

Hi, I am using GROMACS 5.1.4 to simulate water in contact with a surface. I am only interested to calculate some properties of water near the surface. Let's say at a distance of x nm from the...

03 March 2021 9,989 2 View

Enhanced Yellow Fluorescent Protein (Aequorea victoria) DNA sequence?

I am on the lookout for the Enhanced Yellow Fluorescent Protein (Aequorea victoria) DNA sequence. Does anyone know where I can find it? Thank you in advance

03 March 2021 3,568 1 View

What solvent can I used for Paal Knorr reaction between 6-amino hexanoic acid and 2.5 hexanedione?

I am try to make the Paal Knorr reaction between 2.5 hexnedione and 6-amino hexanoic acid, my problem is type of solvent to use, because 6-hexaminohexanoic acid is soluble in water but I am not...

02 March 2021 4,443 2 View

Gel electrophoresis result for total RNA samples, 1.5 Agarose gel was used, How to improve the integrity of RNA?

Gel electrophoresis, RNA degradation, RNA extraction from fresh tissue

02 March 2021 5,433 5 View

Ester cleavage conditions?

Hi all, I need to cleave the ester in Ethyl 2-amino-1H-imidazole-5-carboxylate to make the carboxylic acid and retrieve the product from solution to use in downstream applications of linking to...

01 March 2021 8,766 3 View

Is CD44 degraded in lysosome together with hyaluronan after CD44 mediated endocytosis of hyaluronic acid?

Also when RHAMM binds hyaluronic acid, they get internalized, will RHAMM also be degraded? Or both CD44 and RHAMM will be transferred back to the cell membrane? Asking for breast cancer cell line...

01 March 2021 8,169 2 View

How can I calculate the rdf of water molecules around 'Na' ions that are closest(adsorbed) to the nanoparticle(solute)?

Hi, I want to calculate the radial distribution function for water molecules around the Na+ ions adsorbed on the surface of a spherical nanoparticle using the gromacs trajectory dynamically? For...

28 February 2021 5,650 1 View

What is the most common number of epitopes in an multi-epitope Vaccine?

hi everyone, I'm interested in the field of vaccine design specifically multi-epitope cancer vaccines , I want to know if there is a minimum and maximum number of epitopes we could use in a...

27 February 2021 3,882 3 View

I want to performe MALDI-TOF MS for bacterial identification, I would appreciate it if anyone can tell me the matrix solution preparation protocol ?

based on what I've studied on multiple papers, for peptide and protein identification Alpha-cyano-4-hydroxycinnamic acid (CHCA) is an appropriate matrix to use, I also know that the CHCA powder...

26 February 2021 6,799 3 View

How can I assign a velocity along one direction to CO2 molecules in a molecular dynamics simulation using GROMACS?

Dear all, I am trying to perform a MD simulation about the interaction between CO2 and a polymer. I create my model, solvate it and perform the NVT and NPT equilibration. Now I am not able to...

26 February 2021 10,014 3 View