make the preparation in aqueous 5% sodium bicarbonate (in normal saline). I am giving a simple calculation for 20g mice. You can change it as per your mice weight and desired volume which you want to give (depends on route of administration )-
20mg artesunate in 10ml 5% sodium bicarbonate
use 0.2ml/mice
that will be 20mg/kg
detailed calculation-
20mg/10ml=2mg/ml=0.4mg/0.2ml
if animal having 1kg weight you need 20mg
for 20g weight=20/(1000/20)=20/50=0.2mg
you can adjust the preparation volume, administration volume and dose accordingly