I have continuous measures (n, mean, standard deviation) and counts (n, proportions) that I would like to analyze using a meta analysis. However, rather than comparing these studies to a control group, I would like to compare to normative data. I am using the R metafor package.
For the continuous outcomes (n, mean, standard deviations), the normative means are 100 with a standard deviation of 15. I do not have a sample size associated with the normative data. For the proportions, we have normative data as well. Would anyone be able to provide a suggestion or reference for how to analyze.
For the continuous outcomes, was considering transforming the study mean and standard deviation values into z-scores using the normative means (100) and standard deviations (15):
n=Studyn
z_studyMean = (StudyMean - 100)/15
z_studyStandardDeviation = StudyStandardDeviation/15
Thanks for your assistance.
You might want to employ Meta Essentials which is a free tool https://www.erim.eur.nl/research-support/meta-essentials/ or CMA.
I believe - up to my knowledge- it is not possible to do a meta-analysis without a control group.
I believe you can perform a single-arm meta-analysis for the normative data rather than to a control group.
Here is the guidance that may be helpful for your research.
Article Effectiveness and safety of tacrolimus therapy for myastheni...
Good luck!
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