In order to estimate the urinary 6-sulfatoxymelatonin concentration (ng/h) in children, we collected urinary samples for 24 hours. However, for some of the children, the volume of urine was not reported. There is apparently a way to approximately estimate the urinary volume which I don't know yet. How should I do this ?
Dear friends,
I am a doctor for adult, so sorry about that
Best regards
Thu
I looked into this when you asked the question and could not find the answer. Then, when I saw that you had only had one response, I looked at it again:
Maciel, A. T., & Imed Research Group of Investigators. (2016). Back to Basics: Is There a Good Reason to Not Systematically Measure Urine Creatinine in Acute Kidney Injury Monitoring?. Nephron, 133(2), 111-115.
https://www.karger.com/Article/Fulltext/446666#F01
In the paragraph: Is It Only the Creatinine Concentration in Blood That Matters?
the author writes:
' In simple words, creatinine is increasing in blood because it is not being adequately excreted in urine. The problem may be low urine volume, low CrU concentration or both so that the total mass of excreted creatinine is proportionally low in relation to creatinine production (fig. 1)'.
So there is a link, but I don't think this will be of much help to you?
However, there is the author's email address on the paper and he has a ResearchGate membership. Maybe he might be able to help you?
Dr Alexandre Toledo Maciel
I think this is the same person.
These are some more links; again, perhaps the authors could help:
Kellum, J. A., Sileanu, F. E., Murugan, R., Lucko, N., Shaw, A. D., & Clermont, G. (2015). Classifying AKI by urine output versus serum creatinine level. Journal of the American Society of Nephrology, 26(9), 2231-2238.
Article Classifying AKI by Urine Output versus Serum Creatinine Level
Clark, W. F., Sontrop, J. M., Macnab, J. J., Suri, R. S., Moist, L., Salvadori, M., & Garg, A. X. (2011). Urine volume and change in estimated GFR in a community-based cohort study. Clinical Journal of the American Society of Nephrology, 6(11), 2634-2641.
Article Urine Volume and Change in Estimated GFR in a Community-Base...
This is for the full text:
https://scholar.google.co.uk/scholar?hl=en&as_sdt=0%2C5&q=Urine+Volume+and+Change+in+Estimated+GFR+in+a+Community-Based+Cohort+Study&btnG=
Very best wishes with your PhD,
Mary
Thank you so much for your time and your answer Mary C Wilson. It is very kind of you.
I will definitely read your suggestions and ask the author you mentioned some questions if needed. Again, thank you very much for your help.
Enise
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