How can I put a permanent intrathecal catheter on rats?

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Wenchong Zhang

Sorry, I do fully understand which intrathecal is. Have you try to fix the catheter by dental cement? I have done some operation to fix catheter on skull by dental cement. Or you can tie the catheter by suture to the tissue around.

Jack Haiden Britt

You may wish to look at the method we used for inserting microdialysis catheters. Here is the reference: Concentrations of tumor necrosis factor alpha and progesterone within the bovine corpus luteum sampled by continuous-flow microdialysis during luteolysis in vivo. D W Shaw J H Britt

Biology of Reproduction (Impact Factor: 3.45). 11/1995; 53(4):847-54. DOI: 10.1095/biolreprod53.4.847

Terriann Crisp

I've administered drugs intrathecally in rats with permanent polyethylene catheters for many years. The methods sections of any of my papers could help you with inserting the i.t. catheters. I used a modification of Tony Yaksh's method from the early 1980's. Good luck and let me know if you need help. ... TC