29 October 2020 3 6K Report

Hi everyone,

I struggle to find a single-cell or bulk-sequencing dataset showing the transcriptomic effects of a medical treatment (i.e. COX1 or 2 -inhibition) in patients of inflammatory diseases. My plan is to search for the correlation of the treatment with several genes connected to my project.

I am not a bio-informatician and therefore I depend so far on visualization tools like ( https://immunogenomics.io/ampsle). Most of these tools unfortunately only show cell-specific expression patterns, but no effect of any treatment. I know, analysis tools like https://www.immport.org/home exist - however they don't help without the right dataset.

I already searched through https://singlecell.broadinstitute.org/ or https://www.ebi.ac.uk/gxa/sc/home, but again - I didn't find any dataset with COX-inhibitors. Maybe they include the information which patient got such a treatment, but I don't know how to access that.

Can anyone help me to find/get access to such a dataset?

I hope the solution is not too obvious and I waste your time.

Thank you in advance and cheers,

Peter

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