Hi all,
I'm struggling with selectively removing polystyrene out of a complex of polystyrene and polyvinylpyridine where those are connected with ester crosslinkers.
There is a requirement for the selective cleavage,
1) I cannot use polar solvent
Since I want PVP left and remove only PS using selective solvent, I think I can figure that using toluene would be a good choice to remove polystyrene if I could etch , in non-polar solvent, ester which is a linking part between PVP and PS.
But, I cannot imaging how I can make like a non-polar version of base solvent. For example, base polar solvent is very straightforward like a mixture of water + NaOH.
Can you please share some ideas with me?
Additional curiosity is, is there anyone who knows about or tried TEA for ester hydrolysis?
I hope I can hear some of your opinions on it soon.
Hi Jason,
As you suggested try first toluene and see what comes out.
TEA it is a weak organic base you can try it and see how fast it works on your ester. Another a stonger base LDA (lithium diisopropylamide).
Regards,
Marius
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