How can I create pharmacophore in discovery studio 2.1?

Vishal A Mevada @Vishal-Mevada

06 June 2014 0 3K Report

I would like to create a pharmacoophore model for a set of chemical compounds.

Please let me know the information in detail for a simple process.

Badges
Science topic

Similar topics
Geoscience
Cartography
Mapping

More Vishal A Mevada's questions See All

Is there any published or unpublished statistics on dropout rate (Dose1 to Dose-2) for Covid-19 vaccination in India, US, UK or any other country?

Are there any published or unpublished statistics or papers on the dropout rate (Dose1 to Dose-2) for Covid-19 vaccination in India, USA, UK, or any other country where vaccination has started at...

28 February 2021 4,237 1 View

CUDA Out Of Memory (OOM) error while using GPU?

I'm training a neural network (E3D-LSTM) for spatio temporal video prediction. It's quite a big network that has millions of parameters. The model is training perfectly when using my 12 CPU cores,...

25 December 2020 1,229 3 View

Which area i should focused in FSW of Al-Steel with interlayer?

Can anyone give me suggestion about topic to carry my research? As i see there is number of publication in this area.so i am not getting that which objective i should keep for my research.

04 September 2020 2,286 2 View

Comsol electromagnetic simulation. How to give a mesh for certain micrometer when my tool is in millimeter. The current density is so small. Pls help?

Hi, I am trying to perform mesh convergence and I found out there is no stable temperature value I obtained. So, I calculated the skin depth and it was around 0.00011mm. It is so small in...

24 August 2020 9,060 2 View

Which option (SFA-Cross Or DEA-DMU) is best to measure the individual efficiency (for a sample size of 450 farmers)?

I am working on a set of data, collected from a field survey. I am looking forward to measure the the level of technical efficiency of type of irrigation channels (Solar pump set/ Diesel pump set...

06 August 2020 2,510 3 View

How to increase accuracy in Speech emotions recognition ?

In speech based emotion recognition, for individual artists almost get 90 percentage of accuracy using neural network, but accuracy is decreased up to 70 percentage for entire speech corpus. How...

19 July 2020 4,900 1 View

What are the different methods of estimating snow melt contribution in runoff?

I want to estimate the runoff due to rainfall but the data I have, contains final runoff (i.e. runoff + snowmelt) so is there any method to calculate the contribution of snowmelt in the final...

16 July 2020 6,415 3 View

How to model in COMSOL (Induction heating) . A current applied for 600A for 10 min and continue then 100A for next 5 min. Can someone help me please?

Hi I wanted to model Induction heating in comsol. Apply a current of 600A for 10 minutes in my coil and then a 100A current for 5 minutes. I could not find much of tutorials. I do not know where...

10 April 2020 5,565 12 View

I'm having a hard time to get the UV-vis spectra of acetone. What may be the reason?

I'm getting a weird UV spectra for pure acetone. The analysis were performed on Shimadzu UV-vis spectrophotometer however the graphs weren't good with noise patterns as seen on the image. Any help...

11 November 2019 9,477 5 View

Thermal topology optimization run ends with error due to memory. How to swap memory?

Hello. I had a run error *7007* that the allocated memory is 17,500 Mb but the run for the model required 18,400 Mb. When i check my directory file, there is more memory around 1TB and the system...

06 November 2019 8,994 3 View

What's the best way to measure growth rates in House sparrow chicks from day 2 to day 10?

What's the best way to measure growth rates in House sparrow chicks from day 2 to day 10? Since, the growth curve from day 2 to 10 won't be like the "Logistic curve" it might not follow logistic...

03 March 2021 1,401 3 View

After a reference from Int J Body Compos Res, can any body help?

Hi, I am after the reference below, my library says it cannot obtain a copy either locally or internationally, any help appreciated! Chris Wang ZM, Heshka S, Wielopolski L, Pi-Sunyer FX, Pierson...

03 March 2021 6,193 1 View

What techniques can I use to determine the miscibility of polymer blends?

The term miscibility refers to the single-phase state in thermodynamics. I do not mean the compatibility of different components. To determine the miscibility I know several techniques such as...

03 March 2021 4,107 4 View

How to repeat an operation on an atom selection for multiple times in PyMol?

Hi, I am trying to construct a multi-layer fibril structure from a single layer in PyMol by translating the layer along the fibril axis. For now, I am able to use the Translate command in PyMol...

02 March 2021 4,569 4 View

I am interested in medicinal chemistry field, which books are highly recommended to learn from?

I am at the beginner level in drug design and drug discovery, and I am interested to learn more about this field. Which books are highly recommended to start from and gives me all essential...

02 March 2021 8,437 2 View

Shall I skip the measurement model in SmartPLS?

Hello everyone, I had run a mediation model in SmartPLS using questionnaires that were already validated among my statistical population. A professor who edited my paper -though she is not...

01 March 2021 3,052 3 View

What is involved in morphological changes of SEM images of a substance?

In the sem analysis of CaCO3 nanaoparticles, the morphology images showed spherical shaped particles but the proposed morphology for these type of nanoparticles is trigonal. I prepared the...

01 March 2021 1,960 4 View

Joint behaviour in Abaqus is not captured well?

I am working on roof joint and trying to simulate the behaviour in Abaqus. I am successful in running the model but the final graph does not follow the experimental curve in the negative direction...

01 March 2021 6,661 3 View

How to define tie constraint between rigid body and another part in dynamic explicit model of Abaqus?

Hi dear researchers I connected a rigid body into the part of my structure by tie constraint and then I added displacement to rigid body, in static general step every thing is fine and these two...

28 February 2021 3,442 2 View

Does the circuit modeling for planar monopole antennas using Foster canonical forms give good approximation?

Hi researchers, I am searching for some accurate way to do the circuit modeling of planar CPW-fed monopole antennas. I have gone through the literature where mostly circuit modeling is done using...

28 February 2021 7,016 1 View