How can I calculate the correct dose of levofloxacin?

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If the magnetic direction of any two black holes is made equal. So the capacity of attraction decreases to zero?

If the magnetic direction of any two black holes is made equal. So the capacity of attraction decreases to zero? If it becomes zero. So we can make the ability to magnetize / attract other...

22 December 2020 3,062 4 View

Orthogonal array response vectors in poor scattering mmwave MIMO system?

Can anybody help in understanding how in a MIMO system with large (ideally infinite) number of transmit/receive antennas and poor scattering (e.g at mmWave), the transmit/receive array response...

17 December 2020 6,903 4 View

How to change material in ANSYS & perform brittle deformation ?

I am currently working on a model for fracture generation due to pressure applied in ANSYS. When I am working with structural steel material it is showing only folding not any fracture initiation...

16 December 2020 3,826 3 View

Which is the best Instrument for obtaining the geophysical properties of sub-soil?

For performing the real scenario ground seismic simulation, we require certain input parameters like Shear wave variation with depth or Vs (30), density of the soil layers etc. Following...

29 November 2020 9,714 4 View

How to design the 3D crystal structure of Antibody for protein antigen. Any relevant software/module?

I have a protein (antigen) of size ~ 400 amino acids, for that i need to design antibody 3D PDB file for molecular modelling studies and mechanistic binding analysis to elucidate the molecular...

16 October 2020 4,812 2 View

I want to buy Human Squamous Cell Carcinoma Cell Lines for my phD research .?

i want to buy Human Squamous Cell Carcinoma Cell Lines for my PhD research .? One place is NCCS Pune...Can some give more suggestions..? Humble Regards

20 September 2020 3,940 3 View

How to convert artificial neural network (ANN) regression model into Deep learning model?

A am new to machine learning. I have developed an ANN model with 1 hidden layer, to predict sale forecast. As an assignment I have to prepare Deep Learning model for the same task. Deep model has...

21 May 2020 1,137 4 View

Loop for summation in MATLAB ?

for different values of X, what will be the loop or tool in MATLAB for the below problem summation (U(n-L)(X)*(K(L)-K(L+1)), 1, n-1), where U is the function of X for different time (n-L), and...

18 April 2020 7,047 11 View

Can anyone suggest fast publication in SCI or SCIE indexed journal?

I have a requirement to publish a research paper in Science Citation Index (SCI) or Science Citation Index Expanded (SCIE) indexed journal only in the field of Engineering, Manufacturing,...

27 March 2020 6,625 4 View

How matlab code for test case prioritization is written in genetic algorithm?

I want to write matlab code for test case prioritization using GA? Please suggest

21 September 2019 5,798 2 View

I am interested in medicinal chemistry field, which books are highly recommended to learn from?

I am at the beginner level in drug design and drug discovery, and I am interested to learn more about this field. Which books are highly recommended to start from and gives me all essential...

02 March 2021 8,437 2 View

Does RNAiMAX transfection reagent work in serum free medium?

I diluted siRNA and RNAiMAX in opti-MEM and added to the cells which they were in the growth medium. Is it a right way? or should I culture cells in the opti-MEM medium for a while and not in...

26 February 2021 10,041 3 View

Experimental Design: How deal with pseudreplicates with immunological and clinical-chemical paramaeters?

Hello everybody, I am investigating the influence of a toxinon various clinical-chemical and haematological parameters in fish. I have three treatments (control, low dose, high dose) in my...

24 February 2021 1,243 1 View

How to empty large intestine in mice ?

Hi all I am working on colon-targeted drug delivery for which I kept mice fasting for 6h using fasting grills during scotophase (dark period). I observed liquid fecal content in the cecum and...

23 February 2021 7,701 2 View

Can I use a protein-devoid condition as my negative control in ELISA?

Hello, I am running a sandwich-type ELISA where I am trying to inhibit a protein-protein interaction using small molecules. For each experiment, I determine my Z' (Z-prime) to determine the...

23 February 2021 7,429 1 View

How does the injection volume impact LLOQ and ULOQ in regression analysis (LC-MSMS)?

Hello, I have run into an issue that has sparkled a debate at work: is the LLOQ/ULOQ impacted by injection volume under the following circumstances: 1) Same dilution factor of all samples 2)...

23 February 2021 9,159 3 View

Can two EC50 values with different hill slopes be compared?

Hello, I fit a classical dose response curve Y=Bottom + (Top-Bottom)/(1+10^((LogEC-X)*HillSlope)) to my data (not related to inhibitors etc). The model I use is purely qualitative but it fits...

23 February 2021 8,155 5 View

Which way will be better to give OGT inhibitors doses through intravenous or orally for pregnant female rats and concentration suggestion?

I'm planning to use ST078925 OGT inhibitor from TimTec (OGT-O-linked N-acetylglucosamine (GlcNAc) transferase) for female rats.

16 February 2021 7,850 2 View

Which alginate is best for making gel for wound dressing application?

We are looking into utilizing alginate as a gel coating on an HDPE substrate for drug delivery. I would like to ask the community about their experience with alginate and which commercial sources...

15 February 2021 4,319 4 View

How to calculate the sample size required to detect the difference in pharmacokinetics of methotrexate?

I came across with this study here, https://www.clinexprheumatol.org/abstract.asp?a=5066 And this study says: "The sample size calculation was done to compare two different MTX starting dose...

14 February 2021 3,017 3 View