I know how to use the online tools that will show me the codon usage for my particular organism overall, and for any particular gene. I'd like to determine, in some meaningful & convincing way, whether the usage is different in my gene (or a part of my gene encoding some domain) than from the genome in general. Is there a statistical way to analyze the codon usage tables one can generate? How do people demonstrate, or test whether, their gene's codon usage is different from the rest of the genome? I'm working with bacteria.
That is a simple question for someone currently writing computer code in the field of genomics. A few hours would do it. Data fabricated with a known answer would be needed to validate / debug the program.
Hi Janelle,
If you have a table with codon usage values in lines, and condition in columns (all genome, your gene set), I guess a Wilcoxon test can tell you if the distribution are different or not.
- Badges
- Science topic
- Similar topics
- Biological Science
- Microbiology
- Microorganisms
- Bacteria