According to CFR - Code of Federal Regulations Title 21 of the FDA, instructions specify that the level of aspartame in food products should not exceed 3.5 percent of the weight of the tablet and ensure its purity and safety. You can find more instructions on the FDA. Additionally, it's important to note that aspartame has a synergistic effect with Acesulfame K, and products containing aspartame must be labeled as "contains phenylalanine" to alert individuals with phenylketonuria. Furthermore, the European Food Safety Authority (EFSA) has provided a scientific opinion on aspartame. For the development of food production designs, consulting relevant articles can provide valuable insights. Merve Eşgi

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