My coort of patients have an MRI done for another purpose at assessment and I am wondering if this would be an accurate way of gathering data about sarcopenia in this cohort
I'm in for responses. Interesting and innovative thought.
Four imaging techniques have been used for estimating muscle mass or lean body mass—computed tomography (CT), magnetic resonance imaging (MRI) and dual energy X-ray absorptiometry (DXA). CT and MRI are considered to be very precise imaging systems that can separate fat from other soft tissues of the body, making these methods gold standards for estimating muscle mass in research. High cost, limited access to equipment at some sites and concerns about radiation exposure limit the use of these whole-body imaging methods for routine clinical practice. DXA is an attractive alternative method both for research and for clinical use to distinguish fat, bone mineral and lean tissues. More recently, Ultrasound (US) was introduced as an alternative method to measure muscle mass in limbs.
Maybe this research could help a little bit.
http://jap.physiology.org/content/85/1/115.short
Best regards.
Vedran Markotić
i Think it will depends on the adquisition , the limitation on MRI is movement as you know
MRI has additional limitations: accessibility, cost, claustrophobia,
recently, Ultrasound has been introduced to measure rectus femoris muscle in the assessment of sarcopenia
1. Mueller N, Murthy S, Tainter CR, Lee J, Riddell K, Fintelmann FJ et al. Can Sarcopenia Quantified by Ultrasound of the Rectus Femoris Muscle Predict Adverse Outcome of Surgical Intensive Care Unit Patients as well as Frailty? A Prospective, Observational Cohort Study. Ann Surg. 2016; 264 (6):1116-1124.
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