Our patient is refractory after 3 lines of ICANS post KTE X19 treatment for MCL (dexamethasone, methylprednisolone, anakinra). Has anyone used Dasatinib for neurotoxicity in post CAR T cell use? And if yes, what dose?
Article The tyrosine kinase inhibitor dasatinib acts as a pharmacolo...
Hello all, I have used Amberlite IRC120 H, hydrogen form acidic cation-exchange resin for the ion-exchange of waterglass [sodium silicate solution -- 40% Sodium silicate (mol ratio > 3.2)...
21 February 2021 5,614 3 View
If we want to assess if a phenomenon is going in a direction we expect, we can simulate it, using digital models, possibly agent models factoring in known properties and interaction features. We...
12 February 2021 1,141 21 View
Data sets, when structured, can be put in vector form (v(1)...v(n)), adding time dependency it's v(i, t) for i=1...n and t=1...T. Then we have a matrix of terms v(i, j)... Matrices are important,...
30 January 2021 9,295 6 View
I'm interested in a selective oxidation in an austenitic stainess steel so that Chromia rather then ferrous oxide is formed on top of my metal. I know I should have a value of pO2 around...
16 December 2020 8,541 7 View
Question about the loss of hyperbolicity in nonlinear PDE: when complex eigenvalues appear, what is the effect on flow? I understand that we do not have general results on existence in this case,...
16 December 2020 2,571 3 View
Hi, I am doing TEM routinely in my daily research work. Most of my TEM samples are the inorganic oxide-metal nanocomposite films deposited on single crystal oxide substrate (such as STO, MgO)....
11 December 2020 2,695 5 View
At the cross-roads of Technology for Advanced Manufacturing, involving robots and humans, and Digitised Economic Sectors, is a governance matter for Cognitive Manufacturing [1] and rules of the...
21 November 2020 7,145 20 View
One observation is that in any city (those I know) you have humans, of course, but you also have many animals. Statistics of humans start with population data (for instance demographics) and...
08 November 2020 4,127 6 View
Hello everybody and thank you in advance. I would like to ask you about a power analysis problem starting from an example. I have two medical devices (A and B) that finds lymphnodes. My...
01 November 2020 4,306 11 View
I need the sequence corresponding -3,149 and -3,024 relative to the translational start site of my interest gene. I don't have other info. Can someone help me to understand what I have to...
26 October 2020 325 2 View
Hiiiii everyone! I have an enquiry on statistical analysis. I was looking for many forum and it's still cannot solve my problem. I want to compare means of two groups of data but only with two...
03 March 2021 8,796 3 View
Hi all, I am validating a polyclonal antibody raised against human ANT4, through WB and ICC. In most of my controls, the antibody shows very little off-target binding, but when I pre-incubate the...
03 March 2021 5,999 3 View
03 March 2021 5,360 2 View
I need to prepare a solution of Napabucasin (inhibitor of cancer cell stemness) in dichloromethane. The drug is expensive, so maybe somebody already tried to do it. If it is soluble, what is the...
02 March 2021 9,945 3 View
im working now on TPV solar cells and metamaterials and i realy need our help in CST microwave i have a tpv cell simulation and i want to extract particullarly the absorbtion of only the active...
02 March 2021 2,246 2 View
Hi, I am trying to figure out which test would be most appropriate to run for the following question: Is there a difference in task blood pressure between smokers and non-smokers? There are two...
01 March 2021 8,235 2 View
We have been using Thermo Fisher anti-cardiac Troponin T antibody for immunofluorescence staining in FFPE mouse heart sections but it was recently discontinued. The literature shows it to be the...
01 March 2021 4,937 1 View
I have a set of stably transfected cell lines all transfected with plasmids containing GFP tags on the C terminus. During a western blot using anti-GFP antibody, one of my plasmids has dissociated...
01 March 2021 9,310 4 View
Hi, I am running a size exclusion chromatography experiment with a buffer containing Potassium Acetate as a salt. I analyse these fractions through SDS-PAGE. After boiling my SEC fractions in...
01 March 2021 2,622 3 View
I have used the i-Tasser several times, however it has been unavailable for several days. I tried the swiss-model, but the output was not very pleasant due to the model used. Is there any other...
28 February 2021 4,521 3 View