Only when hemolytic anemia results in a two- to threefold or larger increase in hemoglobin catabolism does jaundice owing to rise of serum unconjugated bilirubin become noticeable. The level of unconjugated bilirubin in the serum hardly ever exceeds 3 to 5 milligrams per 100 ml, even in rapid hemolysis, where the production of bilirubin from hemoglobin reaches the maximum that can be handled, or about six times the normal rate in an adult of 7.5 grams per day (Powell, 1972).

References:

Brain, M. C. (1975, January 1). Hemolysis, jaundice and liver disease. SpringerLink. https://link.springer.com/chapter/10.1007/978-1-4684-2649-6_14

GD;, U. V. R. G. (n.d.). Interference of hemolysis, hyperlipidemia, and icterus on Plasma Infrared Spectral Profile. Analytical and bioanalytical chemistry. https://pubmed.ncbi.nlm.nih.gov/31858169/