Goal is to develop peptide vaccine , peptides are intrinsically linear, what info is gained through the tertiary structure prediction?
The tertiary structure may help you in finding the conformation B cell epitopes. The attached publication may help you further.
Article Structure and Immunogenicity of a Peptide Vaccine, Including...
You may use the latest tertiary structure prediction software for peptides. PEPstrMOD (http://osddlinux.osdd.net/raghava/pepstrmod/)
Thanks to all of your valuable suggestions.....!!
I have hundreds of genes and assigned function for each, many genes in the list performing multiple function, so I have arranged them into 0,1 matrix. I want to make garphical representation of...
09 October 2018 7,934 0 View
Hi all, I am validating a polyclonal antibody raised against human ANT4, through WB and ICC. In most of my controls, the antibody shows very little off-target binding, but when I pre-incubate the...
03 March 2021 5,999 3 View
I did sds page to determine the difference in protein expression between 3 types of vaccine , but i don't have scanner or densitometer available. . so i wonder if there is a software to analyze...
02 March 2021 6,270 3 View
I want to know which of the available Covid-19 Vaccines would elicit the best immunological response and why
02 March 2021 1,388 3 View
It is oftentimes said to be a distinctive metallographic trait that differentiates a fully austenitic and a fully felly ferritic steel without etching that might distinguish between two. Why...
02 March 2021 728 2 View
Dear respective researchers, I was asked by my institution to be vaccinated this week using the sinovac vaccine. However, from some of the information I got, this vaccine is not recommended for...
01 March 2021 7,781 6 View
Millions ask how vaccines of covid 19 be successful and safe, its here to explain generally how vaccine of pfizer work ,mRNA vaccines teach our cells how to make a protein that will trigger an...
28 February 2021 2,723 4 View
I have used the i-Tasser several times, however it has been unavailable for several days. I tried the swiss-model, but the output was not very pleasant due to the model used. Is there any other...
28 February 2021 4,521 3 View
hi everyone, I'm interested in the field of vaccine design specifically multi-epitope cancer vaccines , I want to know if there is a minimum and maximum number of epitopes we could use in a...
27 February 2021 3,882 3 View
Wether vaccine passport declared not to go out of home without it may help taking COVID-19 vaccine. Can't it break individual's right to protect the community? Your comments on perspectives...
27 February 2021 5,549 23 View
Or will we have to get vaccinated every year, as in the case of influenza?
27 February 2021 1,048 5 View