Greeting, colleagues!
Due to high activity of GWAS is it useful to do the whole genome (exome) sequencing for a new target searching in case of drug development? Or is it useful to study gene associates instead of it?
Also will be useful to use genetic data that is collected from patients with adiposity or people with rare disorders (Fabry, Juvenile Hemochromatosis etc) to develop new targets or biomarkers?
Thank you for your help!
https://www.reuters.com/article/us-health-precisionmedicine-insight/how-dna-sequencing-is-transforming-the-hunt-for-new-drugs-idUSKBN0NY0AX20150513
Article Next-generation sequencing in drug development: target ident...
https://sapac.illumina.com/areas-of-interest/genomics-in-drug-development.html
https://www.gsk.com/en-gb/behind-the-science/innovation/how-genomics-is-driving-a-new-era-of-drug-discovery/
As a non initiated, many thanks for this question and the very informative www answers.
Functional genomics seems a major step in the right direction in order to link that massive amount of data to disease processes and.precision medicine. In parallel, essential efforts will be needed from clinicians, to do better and deeper phenomics.
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