Patient aged 37 with no medical history.
Tumor of 4 cm limited to the uterine cervix.
Histology mixed undifferentiated squamous cell carcinom and high grade neuroendocrine carcinom.
Pet scan no metastatic disease.
What is the ideal management?
In this case since NEC of cervix has very dismal prognosis, I would start with cisplatin plus etoposide and consider radiation 3-4 months later, paclitaxel plus cisplatinum or in fragile patients carboplatin instead can be preferred. I recommend HPV evaluation and besides, In these type of rare situations I always suggest second pathologist's opinion.
I think surgery has already been done, if not, I would suggest surgery first
Thank you doctor
I was inquiring about yhe ideal therapeutic sequence.
Surgery than followd by chemoradiation
Or chemoradiation followed by surgery.
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