I have to present the above topic for a panel. Please feel free to discuss any fact, observation, recommendation, related literature regarding Active Pharmaceutical Ingredients, API solubility, poorly soluble APIs, Bioavailability of API...etc.
In order to enhance stability & bioavailability of poorly soluble APIs, there are many strategies can be adopted. For example, Co-solvent (for liquid preparation), Lipid base nano carriers, Solid dispersion, Cyclodextrins (For hydrophobic materials), Particle size reduction, Co-crystallisation, Use of poly-morphs etc.