Hi Folks
Hope all is well with you.
I need a help from you.
I have LLC orthotopic tumor model. We have implanted cell in left lung as usual. We have given treatment.
End point parameters are : Lung weight (left and right separately) and Histopathology H and E to measure the tumor surface area in both lungs.
We are getting expected data with lung weight (right and left both) but H and E area measurements is not correlating with lung wt.
We are also getting biomarker modulation as expected.
Here we are unable to correlate H and E area with efficacy.
How to correlate efficacy and H and E area? Is it reliable correlation for an efficacy?
What are the right end points parameter to correlate the efficacy in Lung orthotopic tumor models.
Please sir help me in this 😔