01 January 1970 0 7K Report

Hi Folks

Hope all is well with you.

I need a help from you.

I have LLC orthotopic tumor model. We have implanted cell in left lung as usual. We have given treatment.

End point parameters are : Lung weight (left and right separately) and Histopathology H and E to measure the tumor surface area in both lungs.

We are getting expected data with lung weight (right and left both) but H and E area measurements is not correlating with lung wt.

We are also getting biomarker modulation as expected.

Here we are unable to correlate H and E area with efficacy.

How to correlate efficacy and H and E area? Is it reliable correlation for an efficacy?

What are the right end points parameter to correlate the efficacy in Lung orthotopic tumor models.

Please sir help me in this 😔

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