Dear Avadhesh Oli, 

check if these papers and their references are of use for you: 

http://www.sciencedirect.com/science/article/pii/S0142961208008156

http://jac.oxfordjournals.org/content/66/4/693.full

Dear Avadesh

We give antimicrobial prophylaxis to reduce the risk of infections. I assume this patient is on prophylaxis because he/she is neutropenic or severely immunocompromised. If that is the case, I would give therapeutic dose of antibiotic to cover the procedure (eg. ciprofloxacin 500mg bd). Once the infection risk has settled down, revert back to prophylactic dose. I hope this helps. Good luck

Siva

Hi Avadesh,

A number of things could significantly increase the risk of post-op infection in your patient; he is elderly, the treatment protocol he may be on presently (especially if dexamethasone or prednisolone is part of it) the disease (particularly if there are significant hypogammaglobulinaemia, and/or neutropaenia) and probably other co-morbidities (such as significant renal impairment). I will suggest your patient gets full (therapeutic) coverage of broad spectrum antibiotics for the procedure and the immediate post-op period, if any of the above (or indeed any other additional infection risk) is present, otherwise the prophylaxis could suffice.

All the best in your work.

John.