I am running bacterial and Candidal MICs using antimicrobial peptides, some of these come in trifluoroacetate salt. I am using a radial diffusion assay technique using TSB agar. Previously, I have used formulations without the salt, but have read it may be bactericidal. Would this TFA salt effect MICs? I am trying to find the salt concentration from the manufacturer as I write this. Thank you!
Samuel Windham
Infectious Disease Fellow
University of Colorado