A definition of total ion current normalisation from https://www.scirp.org/journal/paperinformation.aspx?paperid=86606, i.e. for each feature in the sample, divide its intensity value by the total for the sample.

If I have my features in columns and samples in rows, and for each sample/row I divide the intensity of each feature by the sum of all intensities for that sample (e.g. R code would be ...

TIC

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