RNA Trans-splicing used for repairing of genetic disorders, what about in plants?
Trans-splicing has been described in plant mitochondria and chloroplasts. For example:
The Pentatricopeptide Repeat Gene OTP43 Is Required for trans-Splicing of the Mitochondrial nad1 Intron 1 in Arabidopsis thaliana.Plant Cell (2007) 19: 3256–3265.
Many Independent Origins of trans Splicing of a Plant Mitochondrial Group II Intron. J Mol Evol (2004) 59:80–89
A Pentatricopeptide Repeat Protein Facilitates the trans-Splicing of the Maize Chloroplast rps12 Pre-mRNA. Plant Cell (2006) 18: 2650–2663.
Mutants which do not perform these trans-splicing reactions have severe problems in seed development and germination, and in other cases it may be associated with male sterility.
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