Hello everyine,
Does anybody have a proof (a review or a scietific paper) that indicates if T cells from transgenic mices OT-1 and OT-2 express CD154 on their surface?
I couldnt find the answer on pubmed,
Thank you in advance,
Abhishek Rajput
Both OT1 and OT2 cells, subsets of CD8+ and CD4+ T cells respectively, can express CD154 upon activation. CD154, also known as CD40 ligand, is crucial for T cell activation and interaction with other immune cells, facilitating processes like T-B cell collaboration and enhancing antigen-presenting cell function. Therefore, CD154 expression on OT1 and OT2 cells plays a significant role in their immunological response.
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