Does Leishmania have Calcium-calmodulin dependent phosphodiesterase?

Aakash Mukhopadhyay @Aakash-Mukhopadhyay

10 May 2017 1 7K Report

I am confused with the nomenclature of the phosphodiesterases (PDEs) in trypanosomes like Leishmania. I am aware that PDEs (A, B1, B2, and C) are present in Leishmania however I am not being able to find any reports whether Calcium-calmodulin dependent PDEs are present in Leishmania or not.

On the other hand I did come across one report saying that PDE1 (CaM dependent PDE) activity was not detected in Leishmania.

Any leads?

Muthanna Hadi Hussain

I don't think so.

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