Does latent tuberculosis protect against re-infection?

More Olivier Neyrolles's questions See All

How do one prepare Disulfiram in olive oil solutions?

I have read several articles mentioning the preparation of the drug disulfiram (DSF) in olive oil for oral gavage of rodents. However, in those papers, there is no description of how this is...

06 January 2021 3,810 1 View

What is the black block for Dark Current in a UV-Vis Spectrometer machine? How to insert it in a Spectrometer machine?

I am trying to construct a calibration curve on a new UV-Vis Spectrometer machine (T80+, PG Instruments Ltd). But when I start by setting the parameters using K-Factor method (pressing...

06 October 2020 2,521 3 View

How a devoted health blockchain could effectively identify and track covid-19 patients while preserving the confidentiality of medical records?

Dear colleagues, I am currently working on a health's blockchain able of integrating informations relating to COVID-19 patients. The difficulty is to allow this blockchain to be a general...

21 April 2020 8,492 4 View

Mammary glands in Platypus ?

Dear researchers, Can anyone help me to identify these odd mammary glands in Ornithorynchus anaticus ? I struggle to understand its mecanism : The secretion from all these flat lobes have a...

03 March 2020 8,275 2 View

AnnexinV-FITC/IP staining for apoptosis detection false positive?

HI, I'm currently working on adherent human epithelial cells. In ordrer to evaluate the apoptosis effect of a drug, the cells need to be cultured in a FCS-free medium before the addition of the...

29 January 2020 3,461 3 View

Abaqus Explicit: difference in TEMP, STRESS and PEEQ computation between adiabatic and coupled ?

Hi, I have the two following INP files for Abaqus where the only difference is that in one case I'm using a CAX4R element on the other case, I'm using a CAX4RT element. Solver has been changed...

05 December 2019 5,803 2 View

Why IV curve of outdoor test is linear/?

Hello, I collected data from outdoor test of organic photo voltaic to analyse stability but when plotted current/voltage i got a curve which is difficult to determine Isc, Voc,FF and PCE..can...

11 September 2019 9,552 2 View

How to connect Solar panels and acs712?

Hello all, Please i want to collect data from solar panels using acs712 current sensor but i am a bit confused. solar panels is connected to dc/dc converter with an output to charge battery. so i...

24 July 2019 6,946 4 View

Anyone knows Solar IV curve tracer software?

Hello Researchers, Kindly I am looking for IV curve tracer software for solar project. could you suggest to me a software for this work? Best regards

21 April 2019 2,600 3 View

Modelling for degradation of organic solar cell?

Hello, I am working on the degradation of organic solar cells, can anyone helps with the equation to be used for modelling purpose in Matlab to plot the IV curve. is it possible to use the same...

18 March 2019 9,170 3 View

Which of the Covid-19 Vaccines would elicit the best immunoprotection and why?

I want to know which of the available Covid-19 Vaccines would elicit the best immunological response and why

02 March 2021 1,388 3 View

Experimental Design: How deal with pseudreplicates with immunological and clinical-chemical paramaeters?

Hello everybody, I am investigating the influence of a toxinon various clinical-chemical and haematological parameters in fish. I have three treatments (control, low dose, high dose) in my...

24 February 2021 1,243 1 View

Looking for advices and tips to improve the staining and the gating strategy in human blood?

Hi, I am staining a human blood with CD19, CD3,CD14 and CD16. My gating strategy in FlowJo goes like this: - First, I gate a general population SSC-A VS FSC-A => Then gate for single cells, =>...

21 February 2021 5,724 4 View

Is there a way in which microglia can be extracted from mice without killing them ?

I'm aiming to use an adoptive cell transfer approach, with microglia in mice with ALS. So far all the protocols I have seen, require sacrificing the mouse. I'd like to re-infuse the microglia back...

11 February 2021 9,509 1 View

Can you polarize Jurkat cells into different T helper subsets?

I am wondering if anyone has had success with in vitro polarization (via cytokines) of Jurkat cells. My goal is to understand the affect of a drug on Treg induction and differentiation. I...

12 January 2021 3,606 2 View

Can only the spike protein of the virus provide immunity?

Virology, microbiology, immunology, vaccine

21 December 2020 424 16 View

Can somebody recommend me a decent textbook to learn more about signaling pathways and their mechanistic principles in general?

I studied biochemistry and molecular biology in my bachelors and Immunology in my masters. I never came across a suitable course for general signaling pathways and principles. My interest is...

13 December 2020 5,690 5 View

Is it possible to extract DNA or RNA from paraffinized biopsies ?

My lab have some skin biopsies that were previously conserved in paraffine , and i wanted to know if it is possible to extract DNA or RNA from them.

06 December 2020 7,964 6 View

Could the desmin mutation in myofibrillar myopathy be caused by an infection?

A patient with desminopathy (mutation Thr341Pro DES in a heterozygous state) with the progression of the disease has a decrease in taste and smell, immunosuppression, and an increase in IgA in the...

02 November 2020 5,886 6 View

Whis HLA-A2 TAAs are best for DC pulsation and CD8+ cytotoxic T cell induction?

When looking to establish Ag-specific CD8 cytotoxic T cells with autologous dendritic cells, there are numerous tumor-associated Ags to choose from. Does anybody know which Ags give the best...

27 October 2020 2,068 2 View

Joachim Pimiskern

Maybe the conference lecture was about this study:

https://www.researchgate.net/publication/272514058_Characterization_of_Host_and_Microbial_Determinants_in_Individuals_with_Latent_Tuberculosis_Infection_Using_a_Human_Granuloma_Model

https://www.eurekalert.org/pub_releases/2010-01/uoc--rft011710.php

https://www.eurekalert.org/pub_releases/2015-06/usmc-ied060215.php

Regards,

Joachim

Article Characterization of Host and Microbial Determinants in Indiv...

Jasenko Karamehic

Good and very instructive answer for me and for my daily work colleague Joachim Pimiskern !

Thanks

Thilo Oelert

Essentially, the answer is chronic lung infection is activating, chonic intestinal infection not.

Get the point?