Does it make sense to apply LASSO or another SNP selection algorithm when there are only a few SNPs (around fifteen)?

More Roger Mallol's questions See All

Why do individuals contract a different asbestos related disease when exposed to the same dose and same type?

Exposure to asbestos can result in asbestos related disease such as pleural plaques, pleural thickening, asbestosis, lung cancer and mesothelioma. Assuming a like for like exposure what factors...

09 February 2024 1,526 0 View

Is there a decommodification index calculated for each country in the world?

Esping-Andersen index measures the ability of the state to protect people from being part of "the market", and it is based on pension, sickness and unemployment protection. Few countries have...

29 October 2023 699 1 View

How do I add supplemental material from a published OA paper ?

20 September 2023 6,335 2 View

What differentiates 'energizing music' from up-tempo music in general?

Playlists of functionally-therapeutic music (FTM) for relaxing are in abundance. Where might one find studies focused on 'energizing' FTM recordings?

24 March 2023 6,462 0 View

How to Improve solar panel efficiency?

Buy one of the more efficient solar panel models Buy panels with High Concentrated Photovoltaic (CPV) Cell Avoid installing solar panels in shaded areas Get an expert to install your solar...

13 November 2022 8,391 4 View

Could anyone provide a summary, of what’s going on in these six papers on the holonomy group?

Recently I became aware of ‘The Holonomy Group’. This is to do with how the components of vectors alter, upon their parallel transport in a Riemann space. There are six papers on ‘The Holonomy...

24 August 2022 1,282 1 View

RNA manual method - Trizol (ThermoFisher) and RNAIso Plus (Takara) what is great with Trizol over RNAIso Plus?

I'm isolating RNA using RNAIso Plus (Takara). I need to know what is difference between Trizol and RNAIso Plus. Thanks in advance. Roger JCMR

19 July 2022 6,455 3 View

Suggest best research centers offering training in bisulfite conversion and epigenetics?

Centers in India that offer hands-on training in bisulfite conversion, DNA methylation, expression, and epigenetics are preferred.

24 May 2022 7,867 2 View

Do you have experience with the Maritime Automatic Identification System (AIS)?

I am a member of a FedTech Foundry team investigating AIS enhancements. Our team has developed a short survey (9 questions, estimated time to complete is less than 10...

07 May 2022 322 3 View

How do you create a multi-graph plot labeled for publication using multiclass ROC curves in R?

I'm using RStudio and I keep trying to use plot_grid to create my multiclass ROC graphs, but I keep getting the error: "cannot convert object of class roc to grob." Additionally, each of the...

19 February 2022 1,056 4 View

How to learn more about SPSS and its Application?

I would like to learn more about SPSS and Its application especially in regards to data analysis. Please suggest me how I can learn more about it. Thank you so much.

11 August 2024 9,101 4 View

Can I base on reverse DNA sequences to perform alignment, convert to amino acids and GenBank submission?

I have reverse sequences (AB1 format), can I base on reverse DNA sequences to perform nucleotide alignment, convert nucleotides to amino acids and deposit the sequence in GenBank database?

11 August 2024 5,138 1 View

Baseline drift in HPLC? What causes this?

Hello, Why do i see this baseline drift when i compare my blank (black) to the sample (blue)? Any suggestions as to why this happened? Thank you!

11 August 2024 3,770 4 View

Text-Communication from the M1 Hand Area using BCI—and then there is Elon Musk?

Willett, Shenoy et al. (2021) have developed a brain computer interface (BCI) that used neural signal collected from the hand area of the motor cortex (area M1) of a paralyzed patient. The...

10 August 2024 7,180 0 View

Has anyone applied Python in the field of textile engineering for data analysis, automation, or smart textiles?

I'm currently exploring the application of Python in textile engineering, specifically in areas like data analysis, process automation, and the development of smart textiles. I'm interested in...

10 August 2024 7,429 2 View

Which Scopus Journal provides the most affordable fees?

"PUBLISHING IN A SCOPUS JOURNAL" Researchers are now at a cross road. The critical need to publish in a Scopus or ISI, etc journal is ever vital. Journal Publication fees must be submitted....

10 August 2024 8,621 1 View

Seeking Advice on Viability and Execution of Undergraduate Thesis Topic?

Hello everyone, I am currently developing a thesis proposal and would appreciate your input on its viability and how to effectively carry it out. My proposed topic is: "Does the perceived threat...

10 August 2024 8,992 0 View

How can I use the cif data obtained from rietveld refinement extracted via gsas2, for microstructural analysis using ETEX software?

09 August 2024 7,718 0 View

Who will be moral responsible for the death of thousands of people in the event of an earthquake?

Who will bear moral responsibility for the deaths of thousands of people in the event of an earthquake? Weeks and months remain before the onset of strong earthquakes that bring death to...

08 August 2024 6,134 12 View

How are iso-frequency contours plotted?

Let's say we have a standard, regular hexagonal honeycomb with a 3-arm primitive unit cell (something like the figure attached; the figure is only representative and not drawn to scale). The...

07 August 2024 1,937 1 View

Alessio Valentini

Hi Roger,

15 SNPs are very few for a GWAS. Unless you already selected them around a specific region suspected to harbour some effect. Any technique that will reduce the number of SNPs to be tested is anyway useful (lassp, PLS, PCA and so on)

best wishes, alessio

Roger Mallol

Hi Alessio,

Thanks for your answer.

Best wishes,

Roger