The CDC reports that HIV coinfection can accelerate the course of hepatitis C, including the rapid progression of chronic liver disease from hepatitis C to cirrhosis, a form of permanent liver damage. This is particularly true in people with advanced immunodeficiency (CD4 T-lymphocyte count lower than 200).
Viral hepatitis progresses faster and causes more liver-related health problems among people with HIV than among those who do not have HIV. Liver disease, much of which is related to HBV or HCV, is a major cause of non-AIDS-related deaths among people with HIV.
Up to one-third of HIV-infected patients is infected with the hepatitis C virus (HCV). It is now widely accepted that HIV accelerates the course of HCV-related chronic liver disease.