Concerning the preliminary information regarding the reduction of stroke and thromboembolic events in patients undergoing catheter ablation of AF, what do you think? Do the available studies already suggest a benefit? or is it too soon and we should quitely wait for the results of prospective trials (CABANA) before getting over-enthusiastic?
i think that it is too soon to make such conclusions. the AF ablation was mainly designed to reduce symptomes of AF and should wait for the results of large randomised trials before making such conclusions
There are no proves. Of cours CABANA trial results will be very important.
In my opinion, there are clear expectations, but are yet to be demonstrated
AF increases risk of stroke fivefold. If ablation is successful and stops AF...
I join the opinion that we do not have yet valid proofs. One important issue is how successful AFib ablation is defined - real 100% long-term success can be prooved only by ILR, which is not used in everyday follow-up of such patients. One side-note - the inventor of the maze operation James Cox has reported an extremely low long-term embolic risk after this procedure that is attributed to the exclusion (by excision or closure) of the LA appendage from the blood flow. Exclusion of LAA cannot be done during AFib catheter ablation, so the eventual long-term stroke reduction (if any) would probably be of lower magnitude.
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