We have a lab well suited to analyze vascular function, vasodilation nitric oxide-dependent and independent, roles of eicosanoids, ROS.... And experience.
Thanks, Joaquín García-Estañ. Would you work regarding the activity of my compounds. I synthesized Novel NO donors hybrids, and looking for activity, Please reply
In my lab I currently study non invasively arterial structure and function with reference equipments: an echotracking system for intima-media thickness, diameter, distension and other arterial parameters including baroreceptor sensitivity, sympathetic and parasympathetic activity; a sphygmocor device for pulse wave analysis and central blood pression; FMD studio (Quipu, Pisa, Italy) for the study of flow-mediated vasodilation . Moreover, we measured endothelial precussurs and micro particles as well as several markers of oxidative stress (see my publication with Calabrese V.) and inflammation, including TNF alpha and NGAL.
In our lab we can run this type of in vitro experiment in human blood vessels from both healthy patients and those with type 2 diabetes. Kind regards, David Bunton