Does anyone know where can I download LC-MS libraries?

03 March 2018 0 9K Report

I am looking for characterization of some unknown components probably alkaloid that were extracted from Catharanthus roseus.

Badges
Science topic

Similar topics
Phytochemistry
Extracts

More Mahdi Yahyazadeh's questions See All

How pharmaceutical company separate medicinal alkaloids in big scale?

There are several standards of alkaloids in a company such as sigma with low price. using Chromatography system such as Preparative-HPLC can increase the price of final product. therefore, they...

05 June 2018 8,720 2 View

Is there any correlation between gene expression and protein synthesis?

I am doing qRT-PCR. I would appreciate if any person tell whether the result of qRT-PCR is an indicator for level of protein synthesis.

03 April 2018 5,455 2 View

What is the reproducibility of counter current chromatography (CCC)?

CCC is a preparative method, but I would like to know whether every run likes HPLC have the same retention time or not?

01 February 2018 9,396 1 View

Where can I find a full library of alkaloid analyzed by LC-MS?

I analyzed C. roseus plant extract by LC-MS. I found some unknown peak that I could not find any comparable fragmentation in literature for them. They should probably be alkaloids? How can I...

01 February 2018 2,519 0 View

Strugglling with m6A dot blot any suugesstion ?

I have been doing the m6A dot blot for a while with no improvement, I am extracting the RNA, and I can see the dots although the three biological replicas give a different reading on the memberan...

10 August 2024 8,537 5 View

How can I use the cif data obtained from rietveld refinement extracted via gsas2, for microstructural analysis using ETEX software?

09 August 2024 7,718 0 View

The aqueous fraction of the hydroethanolic extract is showing the presence of palmitic acid. What is the mechanism responsible ?

Palmitic acid presence in aqueous fraction

05 August 2024 8,622 4 View

How can major oxides determined by ICP-MS/ES be normalized to 100% volatile free? How does this connect with LOI?

I am analyzing cherts from different sources found within one specific geologic formation using ICP-MS/ES. My committee was asking this question about my analysis. I was not sure how to answer this

05 August 2024 7,902 3 View

Usage of internal standards in LC-MS/MS analysis?

Have you ever seen a LC-MS/MS method uses both internal standards and external standards (in matrix matching purpose) but the concentrations of internal standards are outside the calibration curve...

05 August 2024 3,083 6 View

Which solvent is better to dissolve with secondary metabolites extracted from fungi?

I work on MCF7 cell cell for anticaner purpose and I wa to do drug preperation the drug ( secondary metabolites extracted from Aspergillus) My question which solvent is better with these secodary...

03 August 2024 4,725 2 View

For systematic review data extraction, should I use ITT or PP analysis, and count all randomized participants or only those who completed the study?

I am conducting a systematic review and meta analysis; as I am extracting data I realized there is a consort diagram that shows the number of patients from randomization till end of the study. So...

01 August 2024 9,992 3 View

For the moringa oleifera extract using ethanol as the solvent,what is the alternative method to concentrate the extract other than rotary evaporation?

99% pure ethanol was used for maceration also alternate methods along with the temperature and time to concentrate the extract can be specified

31 July 2024 5,113 4 View

What are the factors that causes the sample to have higher efficacy at lower concentration?

We conducted an antibacterial study of a plant extract. Varying concentrations of crude extract were subjected to microbroth dilution assay. The result showed that only the lowest concentration of...

31 July 2024 8,666 3 View

What Are the Best Alternatives to the MTT Assay for Assessing Cell Toxicity of Colored Herbal Extracts?

I am currently investigating the cytotoxicity of a series of herbal extracts, and like many studies, I have been using the MTT assay to evaluate cell viability. However, I am encountering a...

31 July 2024 192 4 View