Does anyone know the assay for quantifying the conjugation of Methacrylic anhydride with alginate?

23 August 2017 1 7K Report

I am reacting methacrylic anhydride (MA) with alginate. MA react with OH group of alginate. Is there any assay to quantify the modification?

Mark Krause

You have two types of hydroxyl groups on alginate (alcohol and carboxylic acid), plus you probably have water of hydration. When you add something as reactive as MA you get a big mess.

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